This happens when your memory overpowers your consciousness and you lose your sensitivity. For example, people living in Benares do not feel that it is a sacred place. It is too familiar; that sensitivity is just not there.
How can we preserve that feeling of sacredness in our acts? Through living in the present moment and through sadhana.
Your sadhana will not allow your memory to overpower consciousness. Then repetition is not a hindrance. It is good to feel that some places, times, people and symbols are sacred so that you can be awake and alive. But eventually you need to transcend and feel that the entire creation and your whole life are sacred. For the person of God, the whole world, with all its symbols, places and people are sacred at all times. Be a person of God!